In this video, Prof. Alessandro Gennai addresses one of the most common concerns in facial rejuvenation: how to treat a jawline that has lost its definition. Is it better to opt for aesthetic medicine (fillers) or minimally invasive surgery?
Through the analysis of a real case — a 62-year-old patient — we discover why the key to success lies not in adding volume, but in tissue repositioning and cellular regeneration.
Beyond Filler: Repositioning Instead of Filling
Many patients request fillers to “lift” the face. However, when the cause of the concern is actual structural sagging of the deep tissues, adding volume risks creating a “puffy” and unnatural appearance.
Dr. Gennai explains that the ideal solution in these cases is the mandibular minilift. Unlike a traditional or more extensive neck lift, this procedure focuses on redefining the cervico-mental angle (the jaw-to-neck line) with an extremely delicate approach:
• Minimally invasive access around the ear.
• Suspension of the muscle fascia.
• Removal of excess skin.
The Importance of Regeneration: SEFFILLER®
A structural intervention, however perfect, cannot overlook skin quality. This is where surgery meets regenerative medicine.
Dr. Gennai’s protocol almost always involves combining the minilift with SEFFILLER®, an autologous regenerative therapy technique. This procedure uses the patient’s own stem cells and growth factors to restore skin turgor and vitality from within, without distorting volumes.
What to Expect: Timeline and Results
The goal is not to transform the face, but to return it to its best, freshest version.
• Procedure: Performed under sedation as a Day Hospital case.
• Recovery: Return to social life in approximately 10 days.
• Result: Naturalness, harmony, and respect for facial expression.
The secret to aging gracefully is not the pursuit of artificial perfection, but the ability to support the facial structure with techniques that combine surgical precision and biological regeneration, such as the MIVEL endoscopic lift or the mandibular minilift described in this video.




